A key driver for pushing high-performance computing is the enablement of new research. One of the biggest and most exiting scientific challenge requiring high-performance computing is to decode the human brain. Many of the research topics in this field require scalable compute resources or the use of advance data analytics methods (including deep learning) for processing extreme scale data volumes. GPUs are a key enabling technology and we will thus focus on the opportunities for using these for computing, data analytics and visualisation. GPU-accelerated servers based on POWER processors are here of particular interest due to the tight integration of CPU and GPU using NVLink and the enhanced data transport capabilities.