Discussion and demonstration of the potential with running HPC, and VDI workloads on common clusters for a modern a datacenter Dr. Jekyll and Mr. Hyde scenario. Explore the coexistence of CUDA based HPC or Deep Learning job engines in conjunction with both Linux and Windows machines used for virtual desktop infrastructure. The demonstration will focus on a very minimal VMware vSphere cluster deployment using VSAN storage or RedHat RHVM cluster deployment to host both the Linux HPC multi node cluster for CUDA workloads and a VMware Horizon view or Citrix XenDesktop deployment for Linux and Windows Virtual Desktops performing DirectX, OpenGL, OpenCL, and CUDA based visualization workloads as used by engineering and analysis power users.