In this tutorial, we will discuss AccelerEyes' Jacket software which connects MATLAB to the graphics processing unit (GPU). With the GPU as a backend computation engine, Jacket brings together the best of three important computational worlds: computational speed, visualization, and the user-friendliness of MATLAB programming. Jacket enables developers to write and run code on the GPU in the native M-Language used in MATLAB. Jacket accomplishes this by automatically wrapping the M-Language into a GPU compatible form. By simply casting input data to Jacket's GPU data structure, MATLAB functions are transformed into GPU functions. Jacket also preserves the interpretive nature of the M-Language by providing real-time, transparent access to the GPU compiler. The tutorial will provide examples of running MATLAB code on the GPU for image and signal processing, life science, finance, and other applications. Also, a Q/A session will enable audience members to ask specific questions about the Jacket project and MATLAB GPU computing.